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  • Study reveals how DKK3 triggers smooth muscle cell transformation in aortic aneurysm

    Study reveals how DKK3 triggers smooth muscle cell transformation in aortic aneurysm

    Background

    Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder that primarily affects elderly males. It often develops asymptomatically, yet aneurysm rupture can lead to rapid fatality. Currently, no effective…

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  • Apple Reorganizes Health and Fitness Divisions

    Apple Reorganizes Health and Fitness Divisions

    Apple is reportedly reorganizing some of its divisions as the retirement of former Chief Operating Officer Jeff Williams nears.

    The company will move its health and fitness divisions and place them under the oversight of its services chief,

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  • Researchers identify key role of lactylation in driving aortic dissection

    Researchers identify key role of lactylation in driving aortic dissection

    Recently, a research team led by Professor Jian-Xun Wang and Professor Tao Yu from Qingdao University made a significant breakthrough in understanding the role of lactylation modification in aortic dissection (AD). Their study…

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  • AMD and Sony Tease Next-Gen Graphics, Possibly for a PS6

    AMD and Sony Tease Next-Gen Graphics, Possibly for a PS6

    AMD and Sony jointly teased AMD’s approach to improving its future graphics hardware performance in a video posted to YouTube this week: compression, aggregation and dedication. Compressing all the data in the graphics pipeline for lower memory…

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  • A tangled web of deals stokes AI bubble fears in Silicon Valley

    A tangled web of deals stokes AI bubble fears in Silicon Valley

    Lily JamaliTechnology correspondent, San Francisco

    Getty Images An aerial view of Silicon Valley. There are many buildings, and in the middle of the frame a large circular building in the middle of a park.Getty Images

    Silicon Valley is home to many major tech firms, including Apple’s circular headquarters

    At OpenAI’s DevDay this week, OpenAI boss Sam Altman did what American tech bosses rarely do these days: he actually answered questions from reporters.

    “I know it’s tempting to write the bubble story,” Mr Altman told me as he sat flanked by his top lieutenants. “In fact, there are many parts of AI that I think are kind of bubbly right now.”

    In Silicon Valley, the debate over whether AI companies are overvalued has taken on a new urgency.

    Sceptics are privately – and some now publicly – asking whether the rapid rise in the value of AI tech companies may be, at least in part, the result of what they call “financial engineering”.

    In other words – there are fears these companies are overvalued.

    Mr Altman said he expected investors would make some bad calls and silly start-ups would walk away with crazy money.

    But with OpenAI, he told me, “there’s something real happening here”.

    Not everyone is convinced.

    In recent days, warnings of an AI bubble have come from the Bank of England, the International Monetary Fund, as well as JP Morgan boss Jamie Dimon who told the BBC “the level of uncertainty should be higher in most people’s minds”.

    And here, in what is often considered the tech capital of the world, concerns are growing.

    At a panel discussion at Silicon Valley’s Computer History Museum this week, early AI entrepreneur Jerry Kaplan told a packed audience he has lived through four bubbles.

    Getty Images Jerry Kaplan speaking at an eventGetty Images

    Jerry Kaplan founded Go Corporation, which developed early tablet computers

    He’s especially concerned now given the magnitude of money on the table as compared to the dot-com boom. There’s so much more to lose.

    “When [the bubble] breaks, it’s going to be really bad, and not just for people in AI,” he said.

    “It’s going to drag down the rest of the economy.”

    However, at the Stanford Graduate School of Business, which has minted its fair share of tech entrepreneurs, Prof Anat Admati says while there have been many attempts to model when we’re in the bubble, it can be a futile exercise.

    “It is very hard to time a bubble,” Prof Admati told me. “And you can’t say with certainty you were in one until after the bubble has burst.”

    But the data is concerning to many.

    AI-related enterprises have accounted for 80% of the stunning gains in the American stock market this year – and Gartner estimates global spending on AI will likely reach a whopping $1.5tn (£1.1tn) before 2025 is out.

    Tangled web of deals

    OpenAI, which brought AI into the consumer mainstream with ChatGPT in 2022, is at the centre of the tangled web of deals drawing scrutiny.

    For example – last month, it entered into a $100bn deal with chipmaker Nvidia, which is itself the most valuable publicly traded company in the world.

    It expands an existing investment Nvidia already had in Mr Altman’s company – with expectations that OpenAI will build data centres powered with Nvidia’s advanced chips.

    Then on Monday, OpenAI announced plans to purchase billions of dollars worth of equipment for developing AI from Nvidia rival AMD, in a deal that could make it one of AMD’s largest shareholders.

    Remember this is a private company, albeit one recently valued at a half-trillion dollars.

    Then there’s tech giant Microsoft, which is heavily invested, and cloud computing behemoth Oracle has a $300bn deal with OpenAI, too.

    OpenAI’s Stargate project in Abilene, Texas, funded with the help of Oracle and Japanese conglomerate SoftBank and announced at the White House during President Donald Trump’s first week in office, grows ever larger every few months.

    And as for Nvidia, it has a stake in AI startup CoreWeave – which supplies OpenAI with some of its massive infrastructure needs.

    Getty Images Sam Altman speaking at an event Getty Images

    OpenAI boss Sam Altman

    And as these increasingly complex financing arrangements get more and more common, the experts here in Silicon Valley say they may be clouding perceptions on AI demand.

    Some people aren’t mincing their words about it either, calling the deals “circular financing” or even “vendor financing” – where a company invests in or lends to its own customers so they can continue making purchases.

    “Yes, the investment loans are unprecedented,” Mr Altman told me on Monday.

    But, he added, “it’s also unprecedented for companies to be growing revenue this fast.”

    OpenAI’s revenue is growing quickly, but it has never turned a profit.

    And it is hardly a good sign that the people I’ve spoken to keep bringing up Nortel – the Canadian telecom equipment-maker that borrowed prolifically to help finance deals for their customers (and thereby artificially boost demand for their wares).

    For his part, Nvidia’s Jensen Huang defended his deal with OpenAI on CNBC Monday, saying the firm isn’t required to buy his company’s tech with the money he invests.

    “They can use it to do anything they like,” Huang said.

    “There’s no exclusivities. Our primary goal is just really to support them and help them grow – and grow the ecosystem.”

    Telltale signs

    Mr Kaplan says he sees a couple of telltale signs the AI sector – and therefore the wider economy – could be in trouble.

    In frothy times, he says, companies announce major initiatives and product plans that they don’t yet have the capital for.

    Meanwhile, retail investors clamour to get in on the start-up action.

    The surge in AMD stock this week could indicate investors are trying to get a piece of the ChatGPT wealth machine – and while all this is playing out, real physical infrastructure aimed at satisfying the seemingly insatiable hunger for more AI development is being built.

    “We’re creating a new man-made ecological disaster: enormous data centres in remote places like deserts, that will be rusting away and leaching bad things into the environment, with no one left to hold accountable because the builders and investors will be long gone,” Mr Kaplan said.

    Getty Images Vast buildings being built, with cranes and scaffolding visible over a long landscape.Getty Images

    OpenAI wants to secure $500bn to build a 10-gigawatt complex, under construction in Texas, by the end of this year.

    But even if we are in a bubble, the hope from Silicon Valley is investments being made now won’t necessary go to waste.

    “The thing that comforts me is that the internet was built on the ashes of the over-investment into the telecom infrastructure of yesterday,” said Jeff Boudier, who builds products at the AI community hub Hugging Face.

    “If there is overinvestment into infrastructure for AI workloads, there may be financial risks tied to it,” he said.

    “But it’s going to enable lots of great new products and experiences including ones we’re not thinking about today.”

    There are plenty of believers in AI’s potential to transform society.

    The question is whether the money to fund the ambitions of the foremost companies in the sector may be drying up.

    “Nvidia looks like the last lender or investor,” said Rihard Jarc, who founded the UncoverAlpha newsletter.

    “Who else has the capacity right now to invest $100 billion in another company?”

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  • AI brings hope for cervical cancer detection in rural Africa

    AI brings hope for cervical cancer detection in rural Africa

    AI can be used to detect cervical cancer in women in resource-limited parts of the world. However, for this method to work, investments are needed in healthcare staff, reliable supply chains and trust in these communities. This has…

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  • Genetic study reveals unique mutations in Chinese patients with hypertrophic cardiomyopathy

    Genetic study reveals unique mutations in Chinese patients with hypertrophic cardiomyopathy

    Hypertrophic cardiomyopathy (HCM), a common genetic heart disorder, is often caused by mutations in sarcomere-related genes. While extensively studied in European populations, its genetic basis in Chinese individuals remains poorly…

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  • Geologists discover a deposit of more than 1,000 tons of gold

    Geologists discover a deposit of more than 1,000 tons of gold

    China says a buried trove beneath Hunan’s Wangu gold field could hold more than 1,000 metric tons of gold, with around 300 tons already indicated at shallower levels. The estimate is valued near 600 billion yuan.

    Numbers this big invite…

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  • Apple’s reportedly close to acquiring talent from ‘ambient AI’ startup Prompt AI.

    Apple’s reportedly close to acquiring talent from ‘ambient AI’ startup Prompt AI.

    Apple’s reportedly close to acquiring talent from ‘ambient AI’ startup Prompt AI.

    Follow topics and authors from this story to see more like this in your personalized homepage feed and to receive email…

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  • Tina Wu Named to Fortune Most Powerful Women Asia 2025 List

    SHANGHAI, China, October 13, 2025 – DuPont is proud to announce that Tina Wu, Global Vice President and General Manager for DuPont Mobility & Materials, has been named to Fortune’s Most Powerful Women Asia 2025 list.

    This recognition honors the top 100 women leaders across 14 countries in Asia who are transforming business across Asia’s major industrial, financial, consumer, and technology sectors – where innovation, digitalization and supply chain resilience define competitive advantage. Their innovative strategies and leadership drive market growth, scaling new platforms, and shaping Asia’s business landscape.

    “I’m deeply grateful and proud to be named to the Fortune Most Powerful Women Asia 2025 list. This recognition reflects the strength and impact of the extraordinary women I’ve had the privilege to lead and collaborate with—leaders who continue to inspire, innovate, and drive purposeful change,” said Wu. “To be included among so many influential women from across industries and countries is a privilege. This honor also reflects the colleagues, partners, and mentors I’ve learned from, and collaborated with, along the way.”

    Tina brings deep experience and a track record of driving transformation and growth across a variety of markets including automotive, electronics, packaging, and industrial. She also serves as a Board Director at Glaston Corporation.

    The Most Powerful Women Asia 2025 list and stories are available at this link.

     

    About DuPont

    DuPont (NYSE: DD) is a global innovation leader with technology-based materials and solutions that help transform industries and everyday life. Our employees apply diverse science and expertise to help customers advance their best ideas and deliver essential innovations in key markets including electronics, transportation, construction, water, healthcare and worker safety. More information about the company, its businesses and solutions can be found at www.dupont.com. Investors can access information included on the Investor Relations section of the website at investors.dupont.com.

    About Fortune

    Fortune is a global multi‑platform media company built on a legacy of trusted, award‑winning reporting for those who want to make business better. Fortune measures corporate performance through rigorous benchmarks and holds companies accountable around the world. Its iconic franchises include the Fortune 500, Fortune Global 500, Fortune Southeast Asia 500; Most Powerful Women, and World’s Most Admired Companies; Fortune convenes leaders at world‑class events including the Fortune Global Forum and Brainstorm Tech.

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